Source: FBI Uniform Crime Reports
| Year | Drug Law Arrests | Synthetic Drugs Arrests | % of Drug Law Arrests | % of All Arrests |
| 1970 | 415,600 | 22,858 | 5.5 | 0.3 |
| 1971 | 492,000 | 31,980 | 6.5 | 0.4 |
| 1972 | 527,400 | 46,939 | 8.9 | 0.5 |
| 1973 | 628,900 | 33,332 | 5.3 | 0.4 |
| 1974 | 642,100 | 27,610 | 4.3 | 0.3 |
| 1975 | 601,400 | 28,266 | 4.7 | 0.3 |
| 1976 | 609,500 | 18,285 | 3.0 | 0.2 |
| 1977 | 642,700 | 17,996 | 2.8 | 0.2 |
| 1978 | 628,700 | 16,975 | 2.7 | 0.2 |
| 1979 | 558,600 | 18,434 | 3.3 | 0.2 |
| 1980 | 580,900 | 22,074 | 3.8 | 0.2 |
| 1981 | 559,900 | 20,156 | 3.6 | 0.2 |
| 1982 | 676,000 | 25,012 | 3.7 | 0.2 |
| 1983 | 661,400 | 21,826 | 3.3 | 0.2 |
| 1984 | 708,400 | 19,127 | 2.7 | 0.2 |
| 1985 | 811,400 | 19,474 | 2.4 | 0.2 |
| 1986 | 824,100 | 21,427 | 2.6 | 0.2 |
| 1987 | 937,400 | 25,310 | 2.7 | 0.2 |
| 1988 | 1,155,200 | 31,190 | 2.7 | 0.2 |
| 1989 | 1,361,700 | 28,596 | 2.1 | 0.2 |
| 1990 | 1,089,500 | 22,880 | 2.1 | 0.2 |
| 1991 | 1,010,000 | 22,220 | 2.2 | 0.2 |
| 1992 | 1,066,400 | 20,262 | 1.9 | 0.1 |
| 1993 | 1,126,300 | 20,273 | 1.8 | 0.1 |
| 1994 | 1,351,400 | 22,974 | 1.7 | 0.2 |
| 1995 | 1,476,100 | 32,474 | 2.2 | 0.2 |
| 1996 | 1,506,200 | 30,124 | 2.0 | 0.2 |
| 1997 | 1,583,600 | 41,174 | 2.6 | 0.3 |
| 1998 | 1,559,100 | 45,214 | 2.9 | 0.3 |
| 1999 | 1,557,100 | 48,270 | 3.1 | 0.3 |
| 2000 | 1,579,566 | 52,126 | 3.3 | 0.4 |
| 2001 | 1,586,902 | 65,063 | 4.1 | 0.5 |
| 2002 | 1,538,813 | 67,708 | 4.4 | 0.5 |
| 2003 | 1,678,192 | 77,197 | 4.6 | 0.6 |
| 2004 | 1,745,712 | 89,031 | 5.1 | 0.6 |
| Grand Totals: | 33,732,473 | 1,064,823 | 3.2 | 0.2 |
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