Official Tally and Inclusion Criteria
for Drug-Induced Mortality - 2004

In 2004, a total of 30,711 persons died of drug-induced causes in the United States. p.10

The list of codes included in drug-induced causes was expanded in the 2003 data year to be more comprehensive. Specifically, the following 37 ICD–10 codes were added to the list of drug-induced codes: D52.1, D59.0, D59.2, D61.1, D64.2, E06.4, E16.0, E23.1, E24.2 , E27.3,E66.1, G21.1, G24.0, G25.1, G25.4, G25.6, G44.4, G62.0, G72.0, I95.2, J70.2, J70.3, J70.4, L10.5, L27.0, L27.1, M10.2, M32.0, M80.4, M81.4, M83.5, M87.1, R78.1, R78.2, R78.3, R78.4, and R78.5.

The complete list of causes of death attributable to drug-induced mortality now includes ICD–10 codes:

D52.1, Drug-induced folate deficiency anemia;
D59.0, Drug-induced hemolytic anemia;
D59.2, Drug-induced nonautoimmune hemolytic anemia;
D61.1, Drug-induced aplastic anemia;
D64.2, Secondary sideroblastic anemia due to drugs and toxins;
E06.4, Drug-induced thyroiditis;
E16.0, Drug-induced hypoglycemia without coma;
E23.1, Drug-induced hypopituitarism;
E24.2, Drug-induced Cushing’s syndrome;
E27.3, Drug-induced adrenocortical insufficiency;
E66.1, Drug-induced obesity;

Selected codes from the ICD–10 title Mental and behavioral disorders due to psychoactive substance use, specifically:

F11.0 – F11.5, F11.7 – F11.9, F12.0 – F12.5, F12.7 – F12.9, F13.0 – F13.5, F13.7 – F13.9, F14.0 – F14.5, F14.7 – F14.9, F15.0 – F15.5, F15.7 – F15.9, F16.0 – F16.5, F16.7 – F16.9, F17.0, F17.3 – F17.5, F17.7 – F17.9, F18.0 – F18.5, F18.7 – F18.9, F19.0 – F19.5, F19.7 – F19.9;

G21.1, Other drug-induced secondary parkinsonism;
G24.0, Drug-induced dystonia;
G25.1, Drug-induced tremor;
G25.4, Drug-induced chorea;
G25.6, Drug-induced tics and other tics of organic origin;
G44.4, Drug-induced headache, not elsewhere classified;
G62.0, Drug-induced polyneuropathy;
G72.0, Drug-induced myopathy;
I95.2, Hypotension due to drugs;
J70.2, Acute drug-induced interstitial lung disorders;
J70.3, Chronic drug-induced interstitial lung disorders;
J70.4, Drug-induced interstitial lung disorder, unspecified;
L10.5, Drug-induced pemphigus;
L27.0, Generalized skin eruption due to drugs and medicaments;
L27.1, Localized skin eruption due to drugs and medicaments;
M10.2, Drug-induced gout;
M32.0, Drug-induced systemic lupus erythematosus;
M80.4, Drug-induced osteoporosis with pathological fracture;
M81.4, Drug-induced osteoporosis;
M83.5, Other drug-induced osteomalacia in adults;
M87.1, Osteonecrosis due to drugs;

R78.1, Finding of opiate drug in blood;
R78.2, Finding of cocaine in blood;
R78.3, Finding of hallucinogen in blood;
R78.4, Finding of other drugs of addictive potential in blood;
R78.5, Finding of psychotropic drug in blood;

X40 – X44, Accidental poisoning by and exposure to drugs, medicaments, and biological substances;

X60 – X64, Intentional self-poisoning (suicide) by and exposure to drugs, medicaments, and biological substances;

X85, Assault (homicide) by drugs, medicaments,and biological substances;

Y10 – Y14, Poisoning by and exposure to drugs, medicaments and biological substances,undetermined intent.

Drug-induced causes exclude accidents, homicides, and other causes indirectly related to drug use. Also excluded are newborn deaths associated with mother’s drug use. Note: 41 such deaths were recorded in 2004 -- ICD-10 code P04.4

Numbers of deaths and death rates based on the newly modified list of causes may differ slightly from those previously published. For example, for 2002, the addition of the 37 codes increased the total number of deaths from drug-induced causes from 26,018 to 26,040 (an increase of 22); the total crude and age-adjusted death rates were unaffected.

Source: National Vital Statistics Reports, Volume xx, Number xx April xx, 2007,
Deaths: Final Data for 2004, Page 108, except as indicated

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